22 weeks--past the half way mark

So today I had my second OB appointment and with the results that the anatomy scan and IPS #2 test all came back normal the reality has set in that in 18 weeks I'll be a mama!!

And just to make things more interesting I'll also be a homeowner on Jan. 24--meaning we'll be moving to Innisfil on Feb 2.--nothing like a 7 month old prego moving in the middle of the winter. :) We are extremely excited that 2010 really turned out to be our year and can't wait for the new adventures in 2011.

We have already started planning for the baby's room and since we are not finding out what we are having we decided on a tree/forest themed room with white furniture --lots of owls and woodland creatures to entertain!!--I've been searching on craigslist and kijiji and Im surprised people ever pay full price for stuff when sooo many people are selling almost new items. Needless to say we'll probably end up with an amazing crib for under $200!

here's some pics of the bedding we have--can't wait to paint the room and get organized!

Blood type O may affect infertile women’s chances of pregnancy

From parentcentral.ca

November 04, 2010

Debra Black

Staff Reporter

Researchers at Yale University and Albert Einstein College of Medicine have found an association in infertile women between type O blood and a diminished ovarian reserve, or the number of eggs that can be fertilized and result in pregnancy.
The study found these women with blood type O were at double the risk of having diminished ovarian reserve than women of other blood types, said Sangita Jindal, an assistant professor in the department of Obstetrics & Gynecology and Women’s Health at the Albert Einstein College of Medicine and one of the authors of the study.
But she cautioned: “I don’t want people with Blood Type O to think they’re half as likely to get pregnant. This is only in the infertile population and it’s only an association. We don’t know what the cause is.”
The study of 536 women’s blood types, obtained from data at Yale University under the supervision of Dr. Lubna Pal and data at Albert Einstein College of Medicine, found that both blood type O and A had an association with ovarian reserve.
In the case of infertile women with blood type O, they were twice as likely to have an elevated amount of FSH – a hormone produced by the pituitary gland that is related to the production of estrogen – as well as diminished ovarian/egg reserve, Jindal said in an interview with the Star.
High levels of FSH, or follicle-stimulating hormone, are a key indicator of having a low egg count.
However, researchers found that infertile women with blood type A in the study were 50 per cent less likely to have elevated FSH and diminished reserve, said Jindal who is from Ottawa and did her Ph.D. at the University of Toronto’s Department of Medicine at the Banting and Best Department of Medical Research.
Blood type B failed to demonstrate any relationship with FSH, the study found.
Jindal, also the lab director for the IVF program at Albert Einstein College, stresses it’s too soon to come to any conclusions about what the study’s results mean when it comes to helping infertile couples, which make up about 15 per cent of the population across North America, or one in six couples.
More research must be done to understand what the association means, Jindal said.
The researchers will need to look at blood types and the actual number of eggs produced through IVF in female patients, as well as a number of other variables before they can associate a response to a blood type, she said.
Once that is better understood, doctors working with infertile couples could one day use a woman’s blood type to help determine IVF treatment, Jindal said.
“I think we’re still grappling with why ovaries age. This is another piece of information we bring to the puzzle – yet another association.
“The field is still pretty new.”
The study, which Jindal and her co-authors hope will be published in a journal next spring, was recently presented at the annual American Society for Reproductive Medicine conference in Denver, Colo.

Feeling like I won the lottery

I am almost at the 16 week mark--FOUR MONTHS pregnant and this week I realize just how lucky DH and I am. I've been following all the ladies I cycled with during IVF that resulted in pregnancy--I think there is about 8 or 9 of us---out of 30 or so...each one of us knowing how extremely lucky we were.

While I was browsing around some of the other ivf blogs I just can't belief the amount of heartache and disappointment that goes along with it. I read one woman's story after four ivfs---her cycle yet again has been cancelled due to poor response from her ovaries (even with all those injections pumping in the crazy hormone drugs)--I don't know where they find the strength to keep their chin up and look ahead to the next cycle. 

The odds are low and I knew that going in which just makes me realize just how much of a miracle my lil bean is!!

MIA but back in action

So I realized this morning that I've really put my blogging on hold and I'm not sure what happened...part of me didn't want to write my joy into words in case things took a turn for the worse. As a first time pregger and IVFer I can admit I have been pretty calm about twitches, cramps, aches and pains--I have yet to drive to the ER for confirmation that my bean is still where it should be--BUT throughout my whole first trimester it did sit in the back of my mind that things can go wrong at the most unexpected moment.
Well I am officially onto my second trimester and after an amazing u/s on Tuesday I am feeling more like this is all really happening. The baby was extremely active--so much so the technician had a very difficult time getting the neck measurement. The entire time I had a permanent smile across my face and be amazed at the baby bouncing its feet off my uterine wall (of course I won't be smiling if he/she does that all day once I can feel him/her  LOL)
My symptoms are as strong as ever with nausea (and sickness) getting worse by the weeks---I was hoping week 12 was my saviour but oh no it only gets worse with my poor DH having to witness me losing my breakfast into a bag while we make our morning drive into the city.--no stopping on the express lanes during rush hour :(
I have also just discovered I am anemic--probably from being pregnant but is a HUGE explanation as to why I've been breathless after going up the stairs and a high heart rate (130 resting!)--but no fear it is typical in pregnancy and I'll start a supplement after a second test.
One of the hardest things for me has been being under the care of my family DR. and not my fertility DR. who I trust immensely. I have told my family DR. twice now that I am an IVF patient--every time she fills my blood work form she goes to tick off NO in the IVF box. I just feel like the care isn't up to par and am counting down the days till I get to my OB at Credit Valley Hospital!!
So until Nov. 17th I'll try and stay sane!
This weekend should be a great time for us as we have so much to be thankful for and so much to look forward to. I went on a buffalo shopping trip with my sister and two close friends (all of whom are prego) and couldn't resist buying one little outfit at Carters---a first thanksgiving onezie with a turkey hat--can't wait to show it off next year at the cottage!!
Happy thanksgiving to all the mommas, mommas to be and mommas in waiting!

In-vitro success rates much higher in spring

September 16, 2010

Debra Black

Staff Reporter
The Toronto Star

Spring is often associated with the blossoming of new love. It may also be the best time for in-vitro fertilization.
New research presented at the World Congress on Fertility & Sterility in Munich this week indicates that in-vitro fertilization is almost one and a half times more likely to be successful in March, April and May than in other months.
That may be due to the increased amount of daylight in those months and its impact on women’s hormones, said Dr. Daniela Braga, the lead researcher of the study, which was conducted at the Assisted Fertilization Center in Sao Paolo, Brazil.
“It has been suggested the fertility of animals is increased because of the length of the day,” she said in a phone interview from London. “That probably happens in humans as well.”
Braga, a former veterinarian, had noticed there is a seasonal breeding period in the animal world.
“I used to work with buffalo and cattle,” she said. “We know buffalos are seasonal breeders. We also have noted that there are other mammals that are seasonal breeders, as well as others that are not mammals, such as fish.”
She wondered if the same could apply with humans. So, Braga left her career as a vet, went back to school and studied human reproduction and the biotechnology of reproduction. She eventually joined the team at the Brazilian centre in Sao Paolo.
There, she and a team of researchers looked at the cases of 1,932 women undergoing egg retrieval for intracytoplasmic sperm injection (ICSI), a kind of in-vitro fertilization treatment, during all four seasons.
The results surprised her. While the percentage of developing eggs, high-quality embryos, implantation and pregnancy rates didn’t differ between seasons, the rate of fertilization did.
Specifically, the study found a 1.45-fold increase in the fertilization rate in the spring.
The researchers also measured the levels of different hormones in the female patients and found that the estrogen levels were significantly higher in the spring as well. That increase may be due to the increasing daylight in the spring, she said.
“It is possible that what we are seeing is the effect of changing light on the neurons in the brain which produce gonadotrophin-releasing hormones (GnRH).” That hormone controls the secretion of estrogen from the ovaries, she explained.
The study could ultimately improve the chances of some women getting pregnant, Braga said.
“In practical terms, this may mean that if you are having real difficulty in conceiving, it may be better to have an assisted-reproduction cycle during this season.”

Finally an update!

Sorry its been so long since I've blogged---but we went for our official 7 week u/s and we have one healthy  little bean right where it should be! Leading up to the u/s I was worried about ectopic and then had two days off work for cramping a few days before our appt.---got a bit scared that the embryos had floated back up my tubes--which many people don't realize is still a risk for IVFers. So it was a HUGE relief to see that beating heart right where it should be. (and the cramping can be a side effect of the prometrium)
We have just passed our nine week point--almost 10 weeks and what that means is NO MORE PROMETRIUM!! I know those lil puppies are really good for my uterus lining and the little bean but I will not miss those at all. I'm actually going to have a Farewell Prometrium party (with sparkling juice of course!)

Panel calls for state-funded IVF in Ontario

01 September 2009
By Antony Blackburn-Starza
Appeared in BioNews 523
Leading fertility and adoption experts have called upon the Canadian government to fund three cycles ofIVF for women under 42 in the state of Ontario. The Ontario Expert Panel on Fertility and Adoption, which released its report last week, recommended the province should fund IVF as well as including proposals to reform the adoption system.
The report acknowledged that cost was the major obstacle for those seeking treatment with one cycle costing around $10,000. ‘These recommendations will go a long way toward helping couples face infertility issues - their implementation will make both infertility treatment and adoption more accessible and affordable,' said Beverly Hanck, Executive Director of the Infertility Awareness Association of Canada. Supporters said it was only ‘equitable' to fund fertility treatment as with other medical interventions. ‘What we're advocating is that when your doctor prescribes it, because it is medically necessary, that it should be paid for equitably, not for some and not others,' said Mr. Attaran, professor of law and medicine at the University of Ottawa.
The report also recommended that IVF clinics should be accredited and as part of this be obliged to reduce the multiple birth rate to 15 per cent in five years time and ten per cent within ten years. The multiple birth rate following IVF was 27.5 per cent in 2006. Multiple births pose a risk of health to the mother and baby and the authors of the report said that the high cost of IVF was putting pressure on patients to opt for multiple embryo transfer in the belief this would increase the chances of pregnancy.
In addition, the report estimated that the province could save between $400 to $500 million over the course of the next ten years by reducing the frequency of multiple births. ‘Over a period of years, the savings from those multiple birth incidents would more than cover the cost of public funding of three cycles of IVF,' said the chairman of the panel and president of the University of Waterloo, David Johnston.
A similar postcode lottery in access to IVF treatment exists in the UK, where a report published last month showed that 8 out 10 Primary Care Trusts are failing to provide couples with the full three cycles of IVF treatment recommended by the National Institute for Health and Clinical Excellence (NICE).
A year ago the British Fertility Society (BFS) and the Association of Clinical Embryologists (ACE) introduced new guidelines advising all UK clinics to adopt a single embryo transfer (SET) policy for all women under 37. The move is aimed at reducing the number of risky multiple births amongst IVF patients in the UK.